HerbalZym therapy is a new anti-cancer protocol where a cancer-killing substance is activated by natural enzymatic compounds. Utilizing this new approach to terminal cancer treatment gives those of us who have been treating cancer a weapon that is scientifically sound and well researched. For over 10 years now, over one thousand terminally ill cancer patients have been treated with this therapy with resounding success. We will discuss later the most remarkable things about all of these quite proven natural therapies.
When a cancer cell, or any cell really, grows it activates two different pathways. The first stimulates cellular growth while the second, acting like a safety net, prevents the activated cells from dying from apoptosis (programmed cell death). There is a complex interaction between normal cellular growth and cell death if anything goes wrong. The second pathway protects the cells from dying prematurely. If we want to kill a cell, any cell, we need to activate its growth while inhibiting its ability to protect itself from small or large problems in its biochemistry. So, we want to induce as many problems as we can in its normal growth pathway, while simultaneously blocking its ability to adapt.
There are three “critical pathways” FAS, AKT and TRAIL.
One of these pathways, FAS (fatty acid synthase) is a multi-enzyme it plays a key role in fatty acid synthesis. It is not a single enzyme but a whole enzymatic system composed of 272 kDa multifunctional polypeptide, in which substrates are handed from one functional domain to the next.
FAS is over-expressed is almost all epithelial cancers. Natural agents that inhibit FAS activity induce apoptosis. The over-activation of FAS synthesis in cancer cells is induced by the PI-3K/AKT pathway. This pathway is always active in cancer cells, providing growth stimuli and protection from apoptosis. The prognosis for women with breast cancer is adversely affected by the comorbidities of obesity and diabetes, which are conditions associated with elevated levels of circulating fatty acids, hyperglycaemia and hyperinsulinaemia. A new study shows that abundance of FAS was higher in cancer cells than in normal cells, and was up-regulated by IGF1 in both cell types. IGF-induced growth of normal cells was unaffected by suppression of FAS expression, whereas that of cancer cells was blocked as was their resistance to palmitate-induced cell death. Palmitate did not affect cell proliferation, whereas oleate, an ester or a salt of oleic acid, promoted the growth of normal cells but had the opposite effect, that is, inhibition of IGF1-induced growth of cancer cells. However, when the PI-3K pathway was inhibited, oleate enhanced IGF1-induced growth in both cell types.
Hyperglycaemia conferred resistance on cancer cells, but not on normal cells, to chemotherapy-induced cell death. This resistance was overcome by inhibiting FAS or ceramide production.
AKT, a key regulator of cancer cell growth and survival, is commonly activated in cancers. Activated AKT is oncogenic and required for tumorigenesis in PTEN-deficiecy. However, the importance of AKT in mediating transformation by other oncogenes and which of its targets are necessary for this process are poorly understood. Study shows that there is a feedback regulation between AKT activation and FAS expression. In the past, chemicals that inhibited FAS induced apoptosis. These lead many scientists to speculate that clinical FAS inhibitors should be developed for the treatment of cancer. This isn’t necessary. The inhibition of FAS further inhibits AKT activity. It is the inhibition of AKT activity by the FAS inhibitors that actually induces apoptosis.
We all know that saturated fats are bad for us, right? Wrong. If you have cancer/leukemia, certain saturated fats such as palm oil, coconut oil could be life saving. Remember, oleic acid activates the PI-3K/AKT pathway while palmitate inhibits it, and omega-6 fatty acids fuel cancer growth while omega-3, fish oil and gamma-tocotrienol inhibit it. Oleic acid, the dominant fatty acid in olive oil, promotes cancer cell development. Olive oil consists of 55-85% oleic acid. However, let’s make this very clear. Oleic acid does not cause cancer. It simply promotes the further development of already established cancers.
Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene.
Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40.
Saturated fatty acid-induced apoptosis in MDA-MB-231 breast cancer cells. A role for cardiolipin.
The ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesis.
Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival.
Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes.
Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells.
Effects of omega-3 and omega-6 fatty acids on IGF-I receptor signalling in colorectal cancer cells.
As discussed, inhibiting FAS activity blocks AKT over-expression. We need to increase the dietary content of palmitate in our diets, while simultaneously reducing the level of PI-3K/AKT inducing oleic acid. And we need to activate the enzyme that makes ceramide. We can do this with SinnolZym, CurcuZym, BroccoZym and nicotinamide.
